Background: Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes that requires\nimmediate treatment. Allergic reaction to insulin is rare, especially when using recombinant human insulin. The\nclinical presentation of insulin allergy can range from minor local symptoms to a severe generalized allergic\nreaction such as anaphylaxis. A limited number of cases have been reported on the treatment of severe DKA in\npatients with type 2 diabetes with insulin allergy. Here, we describe a patient with type 2 diabetes with insulin\nallergy in which severe DKA resolved after the initiation of continuous intravenous (IV) recombinant human insulin\ninfusion.\nCase presentation: A 58-year-old man with type 2 diabetes initiated subcutaneous insulin administration (SIA) after\nfailure of oral antidiabetic treatment. Symptoms of an allergic reaction developed, including pruritic wheals\nappearing within 10 min of injection and lasting over 24 h. Both skin prick and intradermal tests were positive with\ndifferent types of insulin. ..................................
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